This itinerary is perfect for first-time visitors eager to experience St. Louis's most famous attractions, from its soaring arch to world-class museums and historic neighborhoods. It balances iconic sights with local flavor, ensuring a memorable introduction to the city's rich heritage and lively atmosphere.
Opening hours, prices and routes can change, so check the details before you set off.
Day 1
5 stops · about 9 hrs
Activity, Viewpoint, Culture, Sightseeing
1
City Museum
Activity
3 hours
Experience a truly unique St. Louis attraction, an interactive museum built from repurposed architectural and industrial objects that delights all ages.
Good to know
Wear comfortable clothes and shoes suitable for climbing and exploring; consider purchasing tickets online in advance, especially on weekends.
2
Gateway Arch National Park
Viewpoint
2 hours
Ascend to the top of the iconic Gateway Arch for breathtaking panoramic views of St. Louis and the Mississippi River, a quintessential first-timer experience.
Good to know
Book tram tickets to the top of the Arch well in advance, especially during peak season, and allow time to visit the museum beneath the Arch.
3
Old Courthouse
Culture
1 hour
Step into history at this beautiful landmark, famous for hosting the Dred Scott case and offering insights into pivotal moments in American justice.
Good to know
Located just a short walk from the Gateway Arch, it's an excellent historical complement to your riverfront exploration.
4
Busch Stadium
Sightseeing
1 hour
Witness the home of the beloved St. Louis Cardinals, a testament to the city's deep passion for baseball and a vibrant downtown landmark.
Good to know
Consider a stadium tour for behind-the-scenes access, or simply admire the exterior and soak in the atmosphere of Ballpark Village nearby.
5
Laclede's Landing
Nightlife
2 hours
Enjoy an evening in St. Louis's only remaining 19th-century commercial district, offering historic charm, dining, and entertainment along the riverfront.
Good to know
This historic district is easily accessible from downtown and offers a variety of restaurants and bars housed in renovated brick warehouses.
Day 2
5 stops · about 11 hrs
Activity, Culture, Nature, Food
6
Saint Louis Zoo
Activity
Half day
Explore one of the nation's leading zoos, renowned for its diverse animal collection and innovative exhibits, all set within the beautiful Forest Park.
Good to know
Admission is free; arrive early to find parking and beat the crowds, especially on weekends and holidays, and wear comfortable walking shoes.
7
Saint Louis Art Museum
Culture
2 hours
Immerse yourself in art from across centuries and cultures at this grand museum, housed in a magnificent Beaux-Arts building in Forest Park.
Good to know
General admission is free, making it an accessible cultural highlight; check for special exhibitions that may require a separate ticket.
8
Missouri History Museum
Culture
2 hours
Delve into the rich history of St. Louis and Missouri, from the Lewis and Clark expedition to the 1904 World's Fair, through engaging exhibits.
Good to know
Admission is free; it's conveniently located within Forest Park, making it easy to combine with other park attractions.
9
Forest Park
Nature
1 hour
Wander through one of the largest urban parks in the United States, home to numerous free attractions and beautiful green spaces, perfect for a leisurely stroll.
Good to know
Utilize the park's free trolley service to navigate between attractions, especially during warmer months, or rent a bike to explore.
10
Central West End
Food
2 hours
Discover a charming, historic neighborhood known for its elegant architecture, tree-lined streets, boutique shops, and diverse dining options.
Good to know
This walkable neighborhood is ideal for an evening meal or a drink after a day in Forest Park, offering a sophisticated atmosphere.
Day 3
5 stops · about 8.5 hrs
Activity, Shopping, Food, Nature
11
Anheuser-Busch Brewery Experience
Activity
2 hours
Take a fascinating tour of the historic Anheuser-Busch brewery, learn about the brewing process, and meet the famous Clydesdales.
Good to know
Tours are popular, so check their website for current offerings and consider booking in advance, especially for specialized tours.
12
Soulard Farmers Market
Shopping
1.5 hours
Immerse yourself in the vibrant atmosphere of one of the oldest public markets west of the Mississippi, offering fresh produce, meats, and local goods.
Good to know
The market is busiest on Saturdays; arrive early for the best selection and to experience its lively energy.
13
The Hill (Italian Neighborhood)
Food
2 hours
Savor authentic Italian cuisine and experience the strong community spirit in this historic neighborhood, famous for its delicious restaurants and bakeries.
Good to know
Plan to have lunch or dinner here; many establishments are family-owned and have been local favorites for generations.
14
Missouri Botanical Garden
Nature
2 hours
Wander through stunning themed gardens, including a traditional Japanese garden and a tropical conservatory, at one of the nation's oldest botanical institutions.
Good to know
Allow ample time to explore the diverse gardens; comfortable walking shoes are recommended for covering the extensive grounds.
15
Cathedral Basilica of Saint Louis
Sightseeing
1 hour
Marvel at the breathtaking mosaics and grand architecture of this magnificent cathedral, one of the largest mosaic installations in the world.
Good to know
Check for tour availability to learn about its history and artistry, and remember to dress respectfully as it is an active place of worship.
Where to stay
Hotels in St. Louis
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